Prevalence of obesity in KSA
Collage of medicine & king Khaled university hospital
Age group (30 – 70 ) years
Between 1995-2000
More than 35.5% are obese of the total population
Drawbacks of obesity
High Blood Pressure
Diabetes
Heart Disease
Dyslipidemia
Bone problems “ osteoarthritis”
Fatty liver
Sleep apnea & depression
Low self-confidence
Unable to perform daily activities
Garcinia quaesita fruit extract helps lose weight
Effect of garcinia quaesita fruit extract
Prevent fat storage
Control appetite
Increase exercise endurance
The Use of Garcinia Extract (Hydroxy Citric Acid) as a Weight loss Supplement
A Systematic Review and Meta-Analysis of Randomized Clinical Trials
2 independent reviewers extracted the data and assessed the methodological quality of included
studies. 23 eligible trials were identified and 12 were included. 9 trials provided data suitable for
statistical pooling
Conclusion
The evidence from RCTs suggests that Garcinia extracts/HCA generate weight loss in the short term.
Gymnema Sylvestre leaf extract helps lose weight
Effect of Gymnema Sylvestre leaf extract
Decrease sugar absorption in the intestine
Stimulate digestion
Increase urine excretion
Effects of a natural extract of (-)-hydroxy citric acid (HCA-SX) and acombination of HCA-SX plus niacin-bound chromium and Gymnema
sylvestre extract on weight loss
Study 60 obese for 8 weeks
Conclusion
garcinia in combination with gymnema sylvestre considered as safe and
effective weight-loss formula that can facilitate a reduction in excess
body weight and BMI
body weight and BMI decreased by 5-6%
Effect of Coleus forskohlii root extract in weight loss
Create Enzyme lipase & adenylate cyclase that decrease body fat without lean on muscle mass “stimulates the release of stored fat from fat cells”
Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men
30 subjects (forskolin, n = 15; placebo, n = 15) were studied in a randomized, double-blind, placebo-controlled study for 12 weeks.
Conclusion
Forskolin was shown to elicit favorable changes in body composition by significantly decreasing body fat percentage and fat mass compared with the placebo group The results indicate that forskolin is a possible therapeutic agent for the management and treatment of obesity.
Chromium picolinate
Effect of Chromium picolinate
Lower blood sugar level
Lower level of body fats
Chromium supplementation in overweight and obesity
systematic review and meta-analysis of randomized clinical trials
39 trials were identified and 20 were included
Conclusion
A meta-analysis of 11 studies showed a statistically significant difference in weight loss favoring chromium over placebo
The evidence from available RCTs shows that chromium supplementation generates statistically significant reductions in body weight.
Choline bitartrate
Effect of Choline bitartrate
Promote faster lipolysis
Burn more fats
Prevent future weight gain & fatty liver
Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes
22 female athletes (15 taekwondo and 7 judo athletes)
Conclusion
Choline supplementation could rapidly reduce body mass without any
side effects on biochemical levels or static strength.
Pyridoxine hydrochloride
Effect of Pyridoxine hydrochloride
Metabolize fat and reduce water retention
Boost immune system
Inositol
Effect of Inositol
Improves insulin sensitivity
References
• https://www.ncbi.nlm.nih.gov/pubmed/15951877
• https://pubmed.ncbi.nlm.nih.gov/16129715/
• https://www.ncbi.nlm.nih.gov/pubmed/15056124
• https://pubmed.ncbi.nlm.nih.gov/23495911/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010674/
• https://www.researchgate.net/publication/8645389_Effects_of_a_natural_extract_of_–hydroxycitric_acid_HCA-SX_and_a_combination_of_HCA-SX_plus_niacin-bound_chromium_and_Gymnema_sylvestre_extract_on_weight_loss
